Endocrine Abstracts

Survival following treatment for childhood malignancy has improved considerably over the last 40 years. Complications of treatment are frequent and although the long-term follow-up of patients is recommended, only 35% of patients are seen regularly. Endocrine complications of cancer therapy, including thyroid dysfunction, are well recognised. The aim of this study is to determine the frequency of hypothyroidism amongst the patients within the Bristish Childhood Cancer Survivor...

Acromegaly and hypopituitarism are associated with elevated standardised mortality ratios (SMR) of between 1.3–3 and 1.2–2.17, respectively. There is little data on the role of hypopituitarism and in particular ACTH deficiency on mortality in patients with acromegaly and less still known about the role of hydrocortisone (HC) replacement. There is data to suggest that previous HC regimens may have overestimated normal cortisol production rates and recent data that hig...